Friday, February 27, 2015

Quantifying Microbiome of self

Here is a very interesting paper that I came across today in Genome Biology Journal. [ ]

The authors took time series data of their microbiota at 10,000 longitudinal data points and concluded that the gut microbiota remains more or less same over a period of time unless there is a real change in life style or disease condition.

For example in the two individuals this study was undertaken, visibly the gut microbiome was upset when the subject visited from developed world to developing world. In case of subject 2 there was a clear change in the gut microbiome pattern when he had bouts of diarrhea [Image below].

It was also reported that the variation between individuals is much larger than variation within an individual [Figure below]